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FLASH GENE
Symbol HS3ST5 contributors: - updated : 19-06-2003
HGNC name heparan sulfate (glucosamine) 3-O-sulfotransferase 5
HGNC id 19419
Location 6q22.31      Physical location : 114.376.750 - 114.384.041
Synonym name heparan sulfate 3-OST-5
Synonym symbol(s) 3OST5, HS3OST5
EC.number 2.8.2.23
DNA
TYPE functioning gene
STRUCTURE 5.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
WISP3 6q22-q23 WNT1 inducible signaling pathway protein 3 TUBE1 6q12 tubulin, epsilon 1 LAMA4 6q21 laminin, alpha 4 LOC345882 6q22.1 similar to Pin2-interacting protein X1 (TRF1-interacting protein 1) (Liver-related putative tumor suppressor) (67-11-3 protein) LOC221278 6q22.1 similar to ret finger protein-like 1 LOC391960 6 similar to 40S ribosomal protein SA (P40) (34/67 kDa laminin receptor) (Colon carcinoma laminin-binding protein) (NEM/1CHD4) (Multidrug resistance-associated protein MGr1-Ag) LOC345884 6q22.1 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) LOC391961 6 similar to fem-1 homolog a (C.elegans) LOC389424 6 similar to Proliferation-associated protein 2G4 (Cell cycle protein p38-2G4 homolog) (hG4-1) LOC391962 6 similar to Cytokine inducible SH2-containing protein 5 (Suppressor of cytokine signaling 5) (SOCS-5) (Cytokine-inducible SH2 protein 6) (CIS-6) LOC389425 6 similar to ribosomal protein S27a LOC221286 6q22.1 similar to ribosomal protein L30 MARCKS 6q21-q22.2 myristoylated alanine-rich protein kinase C substrate FLJ34503 6q22.2 hypothetical protein FLJ34503 HDAC2 6q21 histone deacetylase 2 HS3ST5 6q22.31 heparan sulfate (glucosamine) 3-O-sulfotransferase 5 LOC391963 6 similar to DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4) (DnaJ protein homolog 2) (HSJ-2) (HSDJ) FRK 6q21-q22.3 fyn-related kinase NT5C2L1 6q22.31 5'-nucleotidase, cytosolic II-like 1 COL10A1 6q21-q22.3 collagen, type X, alpha 1(Schmid metaphyseal chondrodysplasia) TSPYL4 6q22.31 TSPY-like 4 RPS5P1 6q22.1-q22.3 ribosomal protein S5 pseudogene 1 TSPYL 6q21-q23 TSPY-like SART2 6q22 squamous cell carcinoma antigen recognized by T cells 2
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
 spinal cord    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period fetal
Text brain
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a short N terminus
  • a single transmembrane segment
  • a consensus sequence for PAPS binding
  • four potential N-glycosylation sites
  • conjugated GlycoP
    HOMOLOGY
    interspecies homolog to Drosophila gpi1
    Homologene
    FAMILY sulfotransferase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS