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FLASH GENE

Symbol

HRC

contributors: mct - updated : 10-04-2018

HGNC name	histidine rich calcium binding protein
HGNC id	5178

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	19q13.3      Physical location : 49.654.457 - 49.658.681

DNA

TYPE	functioning gene
STRUCTURE	4.00 kb     6 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

Y

status

confirmed

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart         Digestive mouth tongue       Hearing/Equilibrium ear         Urinary bladder         Visual eye

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum skeletal

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies

homolog to rabbit Hrc

Homologene

FAMILY

CATEGORY

motor/contractile

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,cytoplasm,organelle,lumen
	intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
text	sarcoplasmic reticulum, luminal
	sarcolemma

basic FUNCTION

may play a role in the regulation of calcium sequestration or release in the sarcoplasmic reticulum of skeletal and cardiac muscle

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

CASQ2, HRC and RYR2 share the same KEKE motif region on the distal part of TRDN (aa 202-231)

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS