Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol HNRNPH3 contributors: npt/ - updated : 18-11-2006
HGNC name heterogeneous nuclear ribonucleoprotein H3 (2H9)
HGNC id 5043
Location 10q22      Physical location : 70.091.767 - 70.102.952
Synonym name core protein 2H9
Synonym symbol(s) 2H9, HNRPH3, FLJ34092
DNA
TYPE functioning gene
STRUCTURE 11.07 kb     10 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text due to their great structural variations the different isoforms may possess differentfunctions in the splicing reaction
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 1332 35.2 331 - Honore
  • two repeats of quasi-RRM (RNP-like (qRRM)) domains
  • 10 exons
  • - splicing 2291 - 297 - Honore
    8 exons
    - splicing - - 215 - Honore
    7 exons
    - splicing 1521 - 145 - Honore
    5 exons
    - splicing 1359 - 139 - Honore
    4 exons
    - splicing 2316 36.9 346 - Honore
  • two repeats of quasi-RRM (RNP-like (qRRM)) domains
  • 10 exons
  • EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    blood / hematopoieticspleen    
    Cardiovascularheart    
    Digestiveliver    
    Endocrinepancreas    
    Nervousbrain   highly
    Reproductivemale systemprostate   
    Respiratorylung    
    Urinarykidney    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Epithelialsecretoryglandularendocrine 
    Epithelialsecretoryglandularexocrine 
    Lymphoid    
    Muscularstriatumskeletal  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    conjugated RiboP
    HOMOLOGY
    intraspecies homolog to HNRPH1
    homolog to HNRPH2
    homolog to HNRPF
    Homologene
    FAMILY
  • heterogeneous nuclear ribonucleoproteins (HNRNP) family
  • CATEGORY RNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm,nuclear bodies
    basic FUNCTION
  • influencing pre-mRNA processing and other aspects of mRNA metabolism and transport
  • involved in the splicing process
  • participating in early heat shock-induced splicing arrest by transiently leaving the hnRNPcomplexes
  • CELLULAR PROCESS nucleotide, RNA splicing
    PHYSIOLOGICAL PROCESS cellular trafficking transport
    PATHWAY
    metabolism nucleic
    signaling
    mRNA metabolism
    a component
  • component of heterogeneous nuclear RNA ribonucleoprotein complex
  • INTERACTION
    DNA
    RNA binding to pre-mRNAs
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS