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FLASH GENE
Symbol HMOX2 contributors: - updated : 28-12-2005
HGNC name heme oxygenase (decycling) 2
HGNC id 5014
Location 16p13.3      Physical location : 4.524.718 - 4.560.347
Synonym symbol(s) HO-2
EC.number 1.14.99.3
DNA
TYPE functioning gene
STRUCTURE 33.00 kb     6 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
two HRM (heme regulatory motif) repeats
HOMOLOGY
Homologene
FAMILY heme oxygenase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,endoplasmic reticulum ,rough,smooth
intracellular,cytoplasm,cytosolic,microsome
basic FUNCTION
  • heme oxygenase-2
  • rate limiting enzyme in the degradation of heme to biliverdin,constitutive form, potent anti-inflammatory proteins whenever oxidation injury takes place
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS