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FLASH GENE
Symbol HMHB1 contributors: np - updated : 02-08-2005
HGNC name histocompatibility (minor) HB-1
HGNC id 29677
Location 5q31.3      Physical location : 143.191.725 - 143.200.282
Synonym name minor histocompatibility antigen HB-1
Synonym symbol(s) HB-1
DNA
TYPE functioning gene
STRUCTURE 8.00 kb     2 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text
  • the translation of this mRNA initiates at a non-AUG (CUG) codon
  • identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    2 - 397 5 41 - -
    EXPRESSION
    Type restricted
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
  • B cell acute lymphoblastic leukemia cells
  • Epstein-Barr virus-transformed B cells
  • fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY antigen
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • playing an important role in the induction of cytotoxic T lymphocyte (CTL) reactivity against leukemia after human histocompatibility leukocyte antigen (HLA)-identical allogeneic bone marrow transplantation (BMT)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS