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FLASH GENE
Symbol HMG2L1 contributors: mct - updated : 20-02-2008
HGNC name high-mobility group protein 2-like 1
HGNC id 5003
Location 22q13.1      Physical location : -
Synonym name protein HMGBCG
Synonym symbol(s) THC211630, HMGBCG
DNA
TYPE functioning gene
STRUCTURE 38.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
Map cen - HMG2L1 - TOM1 - HMOX1 - MCM5 - MB - RBM9 - D22S277 - D22S1142 - D22S278 - D22S1173 - MYH9 - APOL2 - EIF3H - D22S283 - D22S426 - PVALB - NCF4 - CSF2RB - D22S1177 - CSF2RB2 - MPST - TST - IL2RB - SSTR3 /RAC2 - PSCD4 - MFNG - CDC42EP1 - LGALS2 ,SH3BP1 - LGALS1 - qter
Authors Dunham (99)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
11 - 4105 65 601 - Nery (2006)
12 - 4220 - 492 - Nery (2006)
- - 4121 - 492 - Nery (2006)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   highly
Hearing/Equilibriumear   highly
Skin/Tegumentskin   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • two basic DNA binding domains of the HMG box type
  • a C terminal stretch of negatively charged amino-acids
  • HOMOLOGY
    Homologene
    FAMILY HMG1/2 family
    CATEGORY RNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION unknown
    CELLULAR PROCESS nucleotide, chromatin organization
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to manic depressive illness (see MAFD15)
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS