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FLASH GENE
Symbol HLA-DQA2 contributors: KTN - updated : 01/12/2008
HGNC name major histocompatibility complex, class II, DQ alpha 2
HGNC id 4943
Location 6p21.32      Physical location : 3.941.245 - 32.714.664
Synonym name
  • HLA-DQ, alpha chain-related
  • DX alpha chain
  • HLA class II histocompatibility antigen, DQ(6) alpha chain
    • Synonym symbol(s) HLA-DXA, HLA-DQA1
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 6.06 kb     5 Exon(s)
    MAPPING cloned Y linked N status confirmed
    Physical map
    EGFL8 6p21.31 EGF-like-domain, multiple 8 AGPAT1 6p21.3 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha) RNF5 6p21.31 ring finger protein 5 AGER 6p21.3 advanced glycosylation end product-specific receptor PBX2 6p21.3 pre-B-cell leukemia transcription factor 2 C6orf9 6p21.3 chromosome 6 open reading frame 9 NOTCH4 6p21.3 Notch homolog 4 (Drosophila) C6orf10 6p21.3 chromosome 6 open reading frame 10 BTNL2 6p21.3 butyrophilin-like 2 (MHC class II associated) HLA-DRA 6p21.3 major histocompatibility complex, class II, DR alpha HLA-DRB9 6p21.3 major histocompatibility complex, class II, DR beta 9 (pseudogene) HLA-DRB3 6p21.3 major histocompatibility complex, class II, DR beta 3 HLA-DRB2 6p21.3 major histocompatibility complex, class II, DR beta 2 HLA-DRB1 6p21.3 major histocompatibility complex, class II, DR beta 1 HLA-DQA1 6p21.3 major histocompatibility complex, class II, DQ alpha 1 HLA-DQB1 6p21.3 major histocompatibility complex, class II, DQ beta 1 HLA-DQA2 6p21.3 major histocompatibility complex, class II, DQ alpha 2 HLA-DQB2 6p21.3 major histocompatibility complex, class II, DQ beta 2 HLA-DOB 6p21.3 major histocompatibility complex, class II, DO beta TAP2 6p21.3 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) PSMB8 6p21.3 proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional protease 7) TAP1 6p21.3 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) PSMB9 6p21.3 proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional protease 2) PPP1R2P1 6p21.31 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 1 LOC389380 6 LOC389380 HLA-DMB 6p21.3 major histocompatibility complex, class II, DM beta HLA-DMA 6p21.3 major histocompatibility complex, class II, DM alpha BRD2 6p21.3 bromodomain containing 2 HLA-DOA 6p21.3 major histocompatibility complex, class II, DO alpha HLA-DPA1 6p21.3 major histocompatibility complex, class II, DP alpha 1 HLA-DPB1 6p21.3 major histocompatibility complex, class II, DP beta 1 RPL32P1 6p21.3 ribosomal protein L32 pseudogene 1 LOC391913 6 similar to MHC HLA-SX-alpha HLA-DPB2 6p21.3 major histocompatibility complex, class II, DP beta 2 (pseudogene) COL11A2 6p21.3 collagen, type XI, alpha 2
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 1152 27.9 255 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • an Ig-like C1-type (immunoglobulin-like) domain
    • conjugated GlycoP
    HOMOLOGY
    Homologene
    FAMILY
  • MHC class II family
    • CATEGORY antigen
    SUBCELLULAR LOCALIZATION     plasma membrane
    text single-pass type I membrane protein
    basic FUNCTION
  • involved in antigen processing and presentation
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS immunity/defense
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS