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FLASH GENE
Symbol HK3 contributors: mct - updated : 19-04-2008
HGNC name hexokinase 3 (white cell)
HGNC id 4925
Location 5q35.2-q35.3      Physical location : 176.307.870 - 176.326.333
Synonym name ATP:D-hexose 6-phosphotransferase
EC.number 2.7.1.1
DNA
TYPE functioning gene
STRUCTURE 18.00 kb     19 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
Physical map
LOC391851 5 similar to olfactory receptor MOR126-1 LOC389347 5 similar to NY-REN-7 antigen LOC391852 5 similar to MGC68922 protein LOC391853 5 similar to selenophosphate synthetase 1 FLJ44216 5q35.3 FLJ44216 protein KIAA1191 5q35.3 KIAA1191 protein MGC2198 5q35.3 hypothetical protein MGC2198 FLJ39249 5q35.3 ADP-ribosylation factor-like membrane-associated protein HSPC111 5q35.3 hypothetical protein HSPC111 CLTB 4q2-q3 clathrin, light polypeptide (Lcb) ETEA 5q35.3 expressed in T-cells and eosinophils in atopic dermatitis RNF44 5q35.3 ring finger protein 44 PC-LKC 5q35.3 protocadherin LKC KIAA1893 5q35.3 G protein-regulated inducer of neurite outgrowth 1 SNCB 5q35 synuclein, beta LOC253314 5q35.3 similar to eukaryotic translation initiation factor eIF4E-1 MGC14859 5q35.3 hypothetical protein MGC14859 LOC389348 5 LOC389348 KIAA1976 5q35.3 netrin receptor Unc5h1 HK3 5q35.2-q35.3 hexokinase 3 (white cell) RAP80 5q35.3 receptor associated protein 80 JAZ 5q35.3 double-stranded RNA-binding zinc finger protein JAZ FGFR4 5q35.3 fibroblast growth factor receptor 4 NSD1 5q35.1-q35.3 nuclear receptor binding SET domain protein 1 RAB24 5q35.3 RAB24, member RAS oncogene family PX19 5q35.3 px19-like protein MXD3 5q35.3 MAX dimerization protein 3 LMAN2 5q35 lectin, mannose-binding 2 RGS14 5q35.3 regulator of G-protein signalling 14 SLC34A1 5q35.1 solute carrier family 34 (sodium phosphate), member 1 LOC345456 5q35.3 similar to profilin 3 F12 5q35.1 coagulation factor XII (Hageman factor) GPRK6 5q35 G protein-coupled receptor kinase 6 MGC10772 5q35.3 hypothetical protein MGC10772 DBN1 5q35.3 drebrin 1 FLJ22570 5q35.3 Dok-like protein DDX41 5q35.3 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 HSGP25L2G 5q35.3 gp25L2 protein
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
19 - 923 - 923 - Adkins (2002)
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systemuterus   
 female systemplacenta   
Respiratorylung    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Connectiveadipose   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • involved in glycolysis, gluconeogenesis, energy pathways
  • phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS