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FLASH GENE
Symbol HIST2H4A contributors: np - updated : 13-01-2005
HGNC name histone cluster 2, H4a
HGNC id 4794
Location 1q21      Physical location : 149.804.220 - 149.832.725
Synonym name
  • H4 histone, family 2
  • histone 2, H4
  • H4 histone family, member N
  • Synonym symbol(s) H4, H4F2, H4FN, FO108, HIST2H4, H4/n
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 0.00 kb     1 Exon(s)
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 396 11 103 - -
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES basic
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to C.elegans b0035,9
    Homologene
    FAMILY
  • histone H4 family
  • CATEGORY structural protein , DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome,nucleosome
    basic FUNCTION
  • playing a role in the compaction of DNA into nucleosomes
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • core histone H2A/H3B/H3/H4
  • INTERACTION
    DNA approximatively 0.146 kb
    RNA
    small molecule other,
  • interacting with HIV-1 Tat peptides, which allows TAT protein to recruit histone-acetyltranserases to the HIIV-1 LTR
  • protein
  • H2A
  • H2B
  • H3
  • H4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS