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FLASH GENE
Symbol HIST2H2AC contributors: mct/npt - updated : 27-05-2010
HGNC name histone 2, H2ac
HGNC id 4738
Location 1q21.2      Physical location : 149.858.524 - 149.858.960
Synonym name
  • H2A histone
  • histone IIa
  • H2A histone family, member Q
  • Synonym symbol(s) H2A/q, H2AFQ, H2A-GL101, H2A, MGC74460
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 0.44 kb     1 Exon(s)
    Genomic sequence alignment details
    10 Kb 5' upstream gene genomic sequence study
    regulatory sequence Promoter (CAAT box) (TATA box)
    text structure TATA and CAAT boxes in the intergenic promoter region
    MAPPING cloned Y linked N status confirmed
    Physical map
    LOC391095 1 similar to hypothetical protein MGC8902 KIAA0493 1q21.3 KIAA0493 protein LOC388692 1 hypothetical gene supported by AK123662 LOC199882 1q21.3 similar to KIAA0454 protein FCGR1A 1q21.2-q21.3 Fc fragment of IgG, high affinity Ia, receptor for (CD64) HIST2H2BA 1 histone 2, H2ba LOC391096 1 similar to CG31613-PA HIST2H4 1q21 histone 2, H4 HIST2H3A 1 histone 2, H3a HIST2H2AA 1q21 histone 2, H2aa LOC388693 1 hypothetical gene supported by BC005827; NM_003528 HIST2H2BC 1 histone 2, H2bc LOC391097 1 similar to histone protein Hist2h3c1 HIST2H2BE 1q21-q23 histone 2, H2be HIST2H2AC 1q21 histone 2, H2ac HIST2H2AB 1q21 histone 2, H2ab CGI-143 1p36.13-q31.3 CGI-143 protein SV2A 1q21.2 synaptic vesicle glycoprotein 2A SF3B4 1p22.1-p21.3 splicing factor 3b, subunit 4, 49kDa CRA 1q12-q21 cisplatin resistance associated ZA20D1 1q21.3 zinc finger, A20 domain containing 1
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 437 13.8 129 - Zhao (2008)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES basic
    STRUCTURE
    motifs/domains
    mono polymer heteromer , octamer
    HOMOLOGY
    Homologene
    FAMILY
  • histone H2A family
  • CATEGORY DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome,nucleosome
    basic FUNCTION
  • playing a role in the compaction of DNA into nucleosomes
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • core histone H2A/H3B/H3/H4
  • INTERACTION
    DNA approximatively 0.146 kb
    RNA
    small molecule
    protein
  • H2A, H2B, H3, H4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS