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FLASH GENE
Symbol HIST2H2AA3 contributors: np - updated : 15-11-2014
HGNC name histone cluster 2, H2aa3
HGNC id 4736
Location 1q21.2      Physical location : 149.813.785 - 149.823.160
Synonym name
  • H2A histone family, member O
  • histone 2, H2aa
  • histone 2, H2aa3
  • Synonym symbol(s) H2A, H2A.2, H2A/O, H2AFO, H2a-615, HIST2H2AA, H2A/q
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 0.53 kb     1 Exon(s)    1 Copie(s)
    MAPPING cloned   linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 534 14 130 - -
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES basic
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • H2A histone family
  • CATEGORY DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome,nucleosome
    basic FUNCTION
  • playing a role in the compaction of DNA into nucleosomes
  • USP16 and HIST2H2AA3 deubiquitination are critical regulators of embryonic stem cell (ESC) gene expression and differentiation
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • core histone H2A/H3B/H3/H4
  • INTERACTION
    DNA approximatively 0.146 kb
    RNA
    small molecule
    protein
  • H2A
  • H2B
  • H3
  • H4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS