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FLASH GENE
Symbol HIST1H4B contributors: - updated : 12-02-2004
HGNC name histone 1, H4b
HGNC id 4789
Location 6p21.3      Physical location : 26.027.124 - 26.027.480
Synonym name H4 histone family, member I
Synonym symbol(s) H4/I,H4/i,H4FI
DNA
TYPE functioning gene
SPECIAL FEATURE component of a cluster
text I distal cluster
STRUCTURE 0.00 kb     1 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
Physical map
SLC17A2 6p21.3 solute carrier family 17 (sodium phosphate), member 2 TRIM38 6p21.3 tripartite motif-containing 38 HIST1H1PS2 6p21.3 histone 1, H1, pseudogene 2 HIST1H1A 6p22-p21 histone 1, H1a HIST1H3A 6p21.3 histone 1, H3a HIST1H4A 6p21.3 histone 1, H4a HIST1H4B 6p21.3 histone 1, H4b HIST1H3B 6p21.3 histone 1, H3b HIST1H2AB 6p21.3 histone 1, H2ab HIST1H2BB 6p21.3 histone 1, H2bb HIST1H2APS5 6p21.3 histone 1, H2a, pseudogene 5 HIST1H3C 6p21.3 histone 1, H3c HIST1H1C 6p21.3 histone 1, H1c HFE 6p21.3 hemochromatosis
regionally located in the large histone gene cluster
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES basic
STRUCTURE
mono polymer heteromer , octamer
HOMOLOGY
Homologene
FAMILY H4 histone family
CATEGORY DNA associated , transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus,chromatin/chromosome,nucleosome
basic FUNCTION
  • playing a role in the compaction of DNA into nucleosomes
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component core histone H2A/H3B/H3/H4
    INTERACTION
    DNA approximatively 0.146 kb
    RNA
    small molecule
    protein
  • H2A
  • H2B
  • H3
  • H4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS