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FLASH GENE

Symbol

HIST1H2BC

contributors: npt/ - updated : 12-02-2004

HGNC name	histone cluster 1, H2bc
HGNC id	4757

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	6p21.3      Physical location : 26.123.695 - 26.124.132
Synonym name	H2B histone family, member L
	histone 1, H2bc
Synonym symbol(s)	H2B.1, H2B/l, H2BFL, dJ221C16.3, H2B.a/g/h/k/l, MGC104246

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
text	L distal cluster
STRUCTURE	0.44 kb     1 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

regionally located

in the large histone gene cluster

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed HIST1H2BC 1 - 438 14 126 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Blood / hematopoietic bone marrow

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES		basic
STRUCTURE

motifs/domains

mono polymer

heteromer , octamer

HOMOLOGY

interspecies

homolog to C.elegans C50F4.5

Homologene

FAMILY

histone H2B family

CATEGORY

DNA associated , transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,chromatin/chromosome,nucleosome

basic FUNCTION

playing a role in the compaction of DNA into nucleosomes

CELLULAR PROCESS	nucleotide, chromatin organization, remodeling
	nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

component of nucleosomes

INTERACTION

DNA	approximatively 0.146 kb

RNA

small molecule

protein	H2A
	H2B
	H3
	H4

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS