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FLASH GENE
Symbol HIST1H2AH contributors: mct - updated : 05-11-2010
HGNC name histone cluster 1, H2ah
HGNC id 13671
Location 6p22.1      Physical location : 27.114.907 - 27.115.345
Synonym name
  • histone family member
  • histone 1, H2ah
  • core histone family H2A,member S
  • Synonym symbol(s) H2A/S, H2AFALii, dJ86C11.1, H2AFS, HIST1H2AI, MGC171151
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text belonging to a microcluster located between the main terminal and proximal clusters on chromosome 6p
    STRUCTURE 0.49 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    regionally located in a microcluster of histone genes on chromosome 6p21.33
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 439 14 128 - 1999 10384058
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularvessel    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES basic
    STRUCTURE
    motifs/domains
    mono polymer heteromer , octamer
    HOMOLOGY
    Homologene
    FAMILY
  • histone H2A family
  • CATEGORY DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,nucleoplasm
    intracellular,nucleus,chromatin/chromosome,nucleosome
    basic FUNCTION
  • playing a role in the compaction of DNA into nucleosomes
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • part of protein octamer composed of the core histones HIST1H2AH, HIST2H2BE, H3, and H4, forming nucleosomes as the fundamental units of chromatin )
  • INTERACTION
    DNA approximatively 0.146 kb
    RNA
    small molecule
    protein
  • H2A, H2B, H3, H4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS