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FLASH GENE
Symbol HIST1H2AE contributors: npt - updated : 23-09-2004
HGNC name histone cluster 1, H2ae
HGNC id 4724
Location 6p21.3      Physical location : 26.217.147 - 26.217.711
Synonym name
  • histone 1, H2ae
  • histone H2AE
  • H2A histone family, member A
  • Synonym symbol(s) H2A.1, H2A.2, H2A/a, H2AFA
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text a distal cluster
    STRUCTURE 0.56 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Physical map
    HIST1H4C 6p21.3 histone 1, H4c HIST1H1T 6p21.3 histone 1, H1t HIST1H2BC 6p21.3 histone 1, H2bc HIST1H2AC 6p21.3 histone 1, H2ac HIST1H1E 6p21.3 histone 1, H1e HIST1H2BD 6p21.3 histone 1, H2bd HIST1H2BE 6p21.3 histone 1, H2be HIST1H4D 6p21.3 histone 1, H4d HIST1H3D 6p21.3 histone 1, H3d HIST1H2AD 6p21.3 histone 1, H2ad HIST1H2BF 6p21.3 histone 1, H2bf HIST1H4E 6p21.3 histone 1, H4e HIST1H2BG 6p21.3 histone 1, H2bg HIST1H2AE 6p21.3 histone 1, H2ae HIST1H3E 6p21.3 histone 1, H3e HIST1H1D 6p21.3 histone 1, H1d HIST1H4F 6p21.3 histone 1, H4f HIST1H4G 6p21.3 histone 1, H4g HIST1H3F 6p21.3 histone 1, H3f HIST1H2BH 6p21.3 histone 1, H2bh HIST1H3G 6p21.3 histone 1, H3g HIST1H2APS4 6p21.3 histone 1, H2a, pseudogene 4 HIST1H2BI 6p21.3 histone 1, H2bi HIST1H4H 6p21.3 histone 1, H4h
    regionally located in the large histone gene cluster
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 564 14 130 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES basic
    STRUCTURE
    mono polymer heteromer , octamer
    HOMOLOGY
    interspecies homolog to C.elegans Boo35.7
    Homologene
    FAMILY
  • histone H2A family
  • CATEGORY DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome,nucleosome
    basic FUNCTION
  • playing a role in the compaction of DNA into nucleosomes
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component core histone H2A/H3B/H3/H4
    INTERACTION
    DNA approximatively 0.146 kb
    RNA
    small molecule
    protein
  • H2A
  • H2B
  • H3
  • H4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS