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FLASH GENE
Symbol HIST1H2AE contributors: npt - updated : 23-09-2004
HGNC name histone cluster 1, H2ae
HGNC id 4724
Location 6p21.3      Physical location : 26.217.147 - 26.217.711
Synonym name
  • histone 1, H2ae
  • histone H2AE
  • H2A histone family, member A
    • Synonym symbol(s) H2A.1, H2A.2, H2A/a, H2AFA
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text a distal cluster
    STRUCTURE 0.56 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    regionally located in the large histone gene cluster
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 564 14 130 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES basic
    STRUCTURE
    mono polymer heteromer , octamer
    HOMOLOGY
    interspecies homolog to C.elegans Boo35.7
    Homologene
    FAMILY
  • histone H2A family
    • CATEGORY DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome,nucleosome
    basic FUNCTION
  • playing a role in the compaction of DNA into nucleosomes
    • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component core histone H2A/H3B/H3/H4
    INTERACTION
    DNA approximatively 0.146 kb
    RNA
    small molecule
    protein
  • H2A
  • H2B
  • H3
  • H4
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS