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FLASH GENE
Symbol HIST1H2AB contributors: npt - updated : 20/11/2008
HGNC name histone cluster 1, H2ab
HGNC id 4734
Location 6p21.3      Physical location : 26.033.319 - 26.033.796
Synonym name
  • histone 1, H2ab
  • H2A histone family, member M
  • Synonym symbol(s) H2A/m, H2AFM
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    STRUCTURE 0.48 kb     1 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Physical map
    SLC17A2 6p21.3 solute carrier family 17 (sodium phosphate), member 2 TRIM38 6p21.3 tripartite motif-containing 38 HIST1H1PS2 6p21.3 histone 1, H1, pseudogene 2 HIST1H1A 6p22-p21 histone 1, H1a HIST1H3A 6p21.3 histone 1, H3a HIST1H4A 6p21.3 histone 1, H4a HIST1H4B 6p21.3 histone 1, H4b HIST1H3B 6p21.3 histone 1, H3b HIST1H2AB 6p21.3 histone 1, H2ab HIST1H2BB 6p21.3 histone 1, H2bb HIST1H2APS5 6p21.3 histone 1, H2a, pseudogene 5 HIST1H3C 6p21.3 histone 1, H3c HIST1H1C 6p21.3 histone 1, H1c HFE 6p21.3 hemochromatosis
    regionally located in the large histone gene cluster
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 477 14 130 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES basic
    STRUCTURE
    motifs/domains
    mono polymer heteromer , octamer
    HOMOLOGY
    Homologene
    FAMILY
  • H2A histone family
  • CATEGORY DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome,nucleosome
    basic FUNCTION
  • playing a role in the compaction of DNA into nucleosomes
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • core histone H2A/H3B/H3/H4
  • INTERACTION
    DNA approximatively 0.146 kb
    RNA
    small molecule
    protein
  • H2A
  • H2B
  • H3
  • H4
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS