Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol HIST1H1D contributors: npt - updated : 20/11/2008
HGNC name histone cluster 1, H1d
HGNC id 4717
Location 6p21.3      Physical location : 26.234.440 - 26.235.216
Synonym name
  • histone 1, H1d
  • linker histone 1 subtype 3
  • histone H1c
  • H1 histone family, member 3
  • Synonym symbol(s) H1.3, H1F3, MGC138176
    DNA
    TYPE functioning gene
    SPECIAL FEATURE component of a cluster
    text clustered with core histone genes
    STRUCTURE 0.80 kb     1 Exon(s)    single Copie(s)
    10 Kb 5' upstream gene genomic sequence study
    regulatory sequence Promoter (CAAT box) (TATA box)
    text structure highly conserved H1/AC box
    MAPPING cloned Y linked N status confirmed
    Physical map
    HIST1H4C 6p21.3 histone 1, H4c HIST1H1T 6p21.3 histone 1, H1t HIST1H2BC 6p21.3 histone 1, H2bc HIST1H2AC 6p21.3 histone 1, H2ac HIST1H1E 6p21.3 histone 1, H1e HIST1H2BD 6p21.3 histone 1, H2bd HIST1H2BE 6p21.3 histone 1, H2be HIST1H4D 6p21.3 histone 1, H4d HIST1H3D 6p21.3 histone 1, H3d HIST1H2AD 6p21.3 histone 1, H2ad HIST1H2BF 6p21.3 histone 1, H2bf HIST1H4E 6p21.3 histone 1, H4e HIST1H2BG 6p21.3 histone 1, H2bg HIST1H2AE 6p21.3 histone 1, H2ae HIST1H3E 6p21.3 histone 1, H3e HIST1H1D 6p21.3 histone 1, H1d HIST1H4F 6p21.3 histone 1, H4f HIST1H4G 6p21.3 histone 1, H4g HIST1H3F 6p21.3 histone 1, H3f HIST1H2BH 6p21.3 histone 1, H2bh HIST1H3G 6p21.3 histone 1, H3g HIST1H2APS4 6p21.3 histone 1, H2a, pseudogene 4 HIST1H2BI 6p21.3 histone 1, H2bi HIST1H4H 6p21.3 histone 1, H4h
    regionally located in the large histone gene cluster
    RNA
    TRANSCRIPTS type messenger
    text lacking the polyA tail but having instead a palindromic termination element
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    1 - 777 22.2 221 - -
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinesmall intestine   
    Lymphoid/Immunelymph node    
    cell lineage
    cell lines
    fluid/secretion blood
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES basic
    STRUCTURE
    motifs/domains
  • a globular DNA-binding domain
  • a N terminal lysine-rich region
  • a C terminal region with oligopeptide repeats enriched in serine, proline, lysine
  • HOMOLOGY
    interspecies homolog to C.elegans b0414.3
    homolog to murine Hist1h1d
    Homologene
    FAMILY
  • histone H1/H5 family
  • CATEGORY regulatory , DNA associated , transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • involved in basal repression of gene expression
  • playing a role in the condensation of nucleosome chains into higher order structures
  • CELLULAR PROCESS nucleotide, chromatin organization, remodeling
    nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS