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FLASH GENE

Symbol

HDGFRP3

contributors: mct - updated : 20-06-2006

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	15q11.2      Physical location : 83.806.815 - 83.876.321
Genatlas name	hepatoma-derived growth factor, related protein 3
Synonym name	hepatoma-derived growth factor 2
Synonym symbol(s)	HDGF2, CGI-142

DNA

TYPE	functioning gene
STRUCTURE	69.00 kb     6 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 6 - 1973 22 203 - Barrios-Rodiles (2005)

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Cardiovascular heart       moderately Endocrine neuroendocrine pituitary     highly   parathyroid       highly Nervous brain       predominantly Reproductive female system ovary     moderately   male system testis     predominantly Respiratory lung       highly Visual eye anterior segment iris

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a well-conserved amino acid sequence at the N-terminus (the HATH region)
	a putative bipartite nuclear localizing signal (NLS) sequence in a similar location in its self-specific region of HDGF

HOMOLOGY

Homologene

FAMILY

HDGF family

CATEGORY

signaling growth factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION

may function mainly in the nucleus of the brain, testis, and heart, probably for cell proliferation

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS