Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | HCLS1 | contributors: mct - updated : 29-08-2022 |
HGNC name | hematopoietic cell-specific Lyn substrate 1 |
HGNC id | 4844 |
|
Location | 3q13.33 Physical location : 121.350.246 - 121.379.791 |
Synonym name | cortactin-like |
Synonym symbol(s) | HS1, CTTNL, LckBP1, p75 |
DNA |
TYPE | functioning gene |
STRUCTURE | 29.50 kb 14 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
---|
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
---|
|
EXPRESSION |
Type | restricted |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
|
cell lineage | hematopoietic cell lineage |
cell lines | |
fluid/secretion | lymph |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES | Hydrophilic | |
STRUCTURE |
secondary structure | at least six N terminal alpha helices |
conjugated | PhosphoP |
HOMOLOGY |
interspecies | homolog to murine Hcls1 |
homolog to Drosophila cortactin | |
homolog to C.elegans Y45F10D.13 |
Homologene |
FAMILY |
CATEGORY | regulatory , transcription factor |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,organelle,mitochondria | |
intracellular,nucleus,chromatin/chromosome |
CELLULAR PROCESS | nucleotide, transcription, regulation |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling | signal transduction |
a component |
INTERACTION |
DNA | binding |
RNA |
small molecule |
protein | |
|
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
|
Susceptibility |
Variant & Polymorphism | |
Candidate gene |
Marker |
Therapy target |
ANIMAL & CELL MODELS |