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FLASH GENE
Symbol HAUS7 contributors: mct/npt - updated : 18-11-2009
HGNC name HAUS augmin-like complex, subunit 7
HGNC id 32979
Location Xq28      Physical location : 152.713.123 - 152.736.603
Synonym name
  • UCHL5 interacting protein
  • UCH37 interacting protein 1
  • 26S proteasome-associated UCH interacting protein 1
  • expressed-Xq28STS protein
    • Synonym symbol(s) HSXQ28ORF, UCHL5IP, UIP1
    DNA
    TYPE functioning gene
    STRUCTURE 22.97 kb     11 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    11 - 1892 - 368 - Lawo (2009)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • HAUS7 family
    • CATEGORY DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
    text localizes to interphase centrosomes and to mitotic spindle microtubules, and its disruption induces microtubule-dependent fragmentation of centrosomes along with an increase in centrosome size (Lawo 2009)
    basic FUNCTION
  • part of conserved multisubunit protein complex that regulates centrosome and spindle integrity (Lawo 2009)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • Augmin complex (HAUS) is a critical and evolutionary conserved multisubunit protein complex that regulates centrosome and spindle integrity (Lawo 2009)
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS