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FLASH GENE
Symbol HAUS2 contributors: mct/npt - updated : 06-01-2010
HGNC name HAUS augmin-like complex, subunit 2
HGNC id 25530
Location 15q15.1      Physical location : 42.841.010 - 42.862.188
Synonym name
  • chromosome 15 open reading frame 25
  • centrosomal protein 27kDa
  • Synonym symbol(s) C15orf25, FLJ10460, HsT17025, CEP27
    DNA
    TYPE functioning gene
    STRUCTURE 18.99 kb     6 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    5 - 3860 - 204 - Lawo (2009)
    6 - 3953 - 235 - Lawo (2009)
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • augmin family
  • CATEGORY DNA associated
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,peroxisome
    intracellular,cytoplasm,cytosolic
    intracellular,cytoplasm,cytoskeleton,microtubule,centrosome
    intracellular,cytoplasm,cytoskeleton,microtubule,mitotic spindle
    basic FUNCTION
  • part of conserved multisubunit protein complex that regulates centrosome and spindle integrity (Lawo 2009)
  • plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis (Uehara 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • augmin complex (HAUS) is a critical and evolutionary conserved multisubunit protein complex that regulates centrosome and spindle integrity (Lawo 2009)
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS