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FLASH GENE

Symbol

HAPLN3

contributors: np - updated : 05-01-2005

HGNC name	hyaluronan and proteoglycan link protein 3
HGNC id	21446

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	15q25.3      Physical location : 89.420.519 - 89.438.770
Synonym name	extracellular link domain containing, 1
Synonym symbol(s)	HsT19883, EXLD1

DNA

TYPE	functioning gene
SPECIAL FEATURE	component of a cluster
text	component of a cluster of paralogous genes in chromosomes 15 and 19
STRUCTURE	18.00 kb     5 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

provisional

Map	see TM6SF1

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed HAPLN3 5 - 1893 40 360 - -

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Lymphoid/Immune thymus         Nervous brain         Reproductive female system breast       Visual eye retina

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a immunoglobulin-like V-type domain
	two link domains

HOMOLOGY

intraspecies

paralog to EXLD2P

Homologene

FAMILY	hyaluronan and proteoglycan binding link protein gene family
	immunoglobulin subtype family

CATEGORY

adhesion

SUBCELLULAR LOCALIZATION

extracellular

basic FUNCTION	may function in hyaluronic acid binding and cell adhesion
	stabilizing the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS