Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol HAGHL contributors: KTN/npt - updated : 05/11/2008
HGNC name hydroxyacylglutathione hydrolase-like
HGNC id 14177
Location 16p13.3      Physical location : 776.957 - 779.715
Synonym name GLO2-like/ RJD12
Synonym symbol(s) MGC2605
EC.number 3.1.2.6
DNA
TYPE functioning gene
STRUCTURE 2.76 kb     11 Exon(s)
MAPPING cloned Y linked N status confirmed
Physical map
SOLH 16p13.3 small optic lobes homolog (Drosophila) LOC146325 16p13.3 similar to hypothetical protein FLJ13841 FLJ36208 16p13.3 hypothetical protein FLJ36208 PIGQ 16p13.3 phosphatidylinositol glycan, class Q RAB40C 16p13.3 RAB40C, member RAS oncogene family WFIKKN 16p13.3 RAB40C, member RAS oncogene family MGC13114 16p13.3 hypothetical protein MGC13114 LOC388198 16 LOC388198 MGC15416 16p13.3 hypothetical protein MGC15416 KIAA1924 16p13.3 hypothetical protein KIAA1924 LOC197336 16p13.3 similar to RIKEN cDNA 3230401M21 [Mus musculus] ARHT2 16p13.3 ras homolog gene family, member T2 RHBDL1 16p13.3 rhomboid, veinlet-like 1 (Drosophila) STUB1 16p13.3 STIP1 homology and U-Box containing protein 1 LOC339123 16p13.3 similar to RIKEN cDNA 2610003J06 DKFZp434F054 16p13.3 hypothetical protein DKFZp434F054 MGC33974 16p13.3 hypothetical protein MGC33974 MGC2601 16p13.3 hypothetical protein MGC2601 MGC2494 16p13.3 hypothetical protein MGC2494 FLJ34512 16p13.3 hypothetical protein FLJ34512 HAGHL 16p13.3 hydroxyacyl glutathione hydrolase-like NARFL 16p13.3 nuclear prelamin A recognition factor-like MSLN 16p13.3 mesothelin RLUCL CHTF18 16p13.3 CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) GNG13 16p13.3 guanine nucleotide binding protein (G protein), gamma 13 LOC388199 16 LOC388199 FLJ12681 16p13.3 hypothetical protein FLJ12681
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
7 splicing 1728 31.4 290 - -
8 splicing 1379 31.1 282 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineparathyroid   moderately
Lymphoid/Immunethymus   moderately
Reproductivefemale systemuteruscervix highly
cell lineage
cell lines
fluid/secretion predominantly in lymph
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to dog HAGHL (88.8 pc)
homolog to chimpanzee HAGHL (83.4 pc)
homolog to murine Haghl (82.7 pc)
homolog to chicken HAGHL (67.3 pc)
Homologene
FAMILY
  • metallo-beta-lactamase superfamily
  • glyoxalase II family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • being an hydrolase acting on ester bonds
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule metal binding, cofactor,
  • Zn2+ (binding 2 ions per subunit)
  • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS