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FLASH GENE
Symbol HABP4 contributors: mct - updated : 26/09/2008
HGNC name hyaluronan binding protein 4
HGNC id 17062
Location 9q22.3-q31      Physical location : 99.212.413 - 99.253.617
Synonym name
  • intracellular hyaluronan binding protein
  • chromodomain helicase DNA binding protein 3 interacting protein
  • intracellular antigen detected by monoclonal antibody Ki-1
  • Synonym symbol(s) KI1, IHABP4, Ki-1/57, MGC825, SERBP1L
    DNA
    TYPE anonymous DNA segment
    STRUCTURE 41.20 kb     8 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    FANCC 9q22.3 Fanconi anemia, complementation group C PSMA7P 9q22.31 proteasome (prosome, macropain) subunit, alpha type, 7 pseudogene LOC375748 9q22.33 RAD26L hypothetical protein, alternatively spliced product; similar to (AF217319) putative repair and recombination helicase RAD26L [Mus musculus] LOC56959 9q22.33 hypothetical protein from EUROIMAGE 2005326 LOC158435 9q22.33 hypothetical protein BC008050 LOC286000 9q22.33 similar to hypothetical protein BC007171 HSD17B3 9q22.3 hydroxysteroid (17-beta) dehydrogenase 3 SLC35D2 9q22.33 solute carrier family 35, member D2 ZNF367 9q22 zinc finger protein 367 HABP4 9q22.3-q31 hyaluronan binding protein 4 CDC14B 9q22.32 CDC14 cell division cycle 14 homolog B (S. cerevisiae) C9orf21 9q22.32 chromosome 9 open reading frame 21 LOC286355 9q22.33 similar to hypothetical protein ZNF510 9q22.33 zinc finger protein 510 LOC158431 9q22.33 similar to zinc finger protein 11b (KOX 2) LOC347262 9q22.33 similar to hypothetical protein FLJ40432 LOC392369 9 similar to hypothetical protein HIATL2 9q22.33 hippocampus abundant gene transcript-like 2 CTSL2 9q22.2 cathepsin L2 TCEA1P 9q22.33 transcription elongation factor A (SII), 1 pseudogene LOC340508 9q22.33 hypothetical protein LOC340508 LOC389776 9 similar to RIKEN cDNA 2810453I06 LOC392370 9 similar to SNAG1 KIAA1529 9q22.33 KIAA1529 LOC389777 9 LOC389777 LOC286359 9q22.33 hypothetical protein LOC286359 PCTAIRE2BP 9q22.33 tudor repeat associator with PCTAIRE 2 TMOD1 9q22.32-q22.33 tropomodulin 1 LOC158427 9q22.33 PP4189 NCBP1 9q34.1 nuclear cap binding protein subunit 1, 80kDa XPA 9q22.32 xeroderma pigmentosum, complementation group A LOC392371 9 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) FOXE1 9q22.3 forkhead box E1 (thyroid transcription factor 2) NAP1 19q13.33 pronapsin A
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    8 - 2708 - 413 - Passos (2006)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouthtongue  highly
    Nervousbrain    
    Visualeye   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    physiological period pregnancy
    Text placenta
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • two conserved Gly/Arg-rich motif clusters (RGG/RXR box, that may be substrates for arginine-methylation by PRMT1
  • HOMOLOGY
    interspecies ortholog to chicken
    ortholog to murine Ihabp4
    intraspecies paralog to CDC37
    paralog to SERBP1
    Homologene
    FAMILY
    CATEGORY regulatory , antigen
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    intracellular,nucleus
    basic FUNCTION
  • putative regulator of cell cycle
  • with SERBP1, might be involved in nuclear functions like the remodeling of chromatin
  • CELLULAR PROCESS cell cycle
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • interacting with the C-terminal region of the chromatin-remodeling factor CHD3
  • interacting with PRMT1
  • partner of MEF2C protein and may be involved in the regulation of MEF2C at the onset of hypertrophy
  • cell & other
    REGULATION
    induced by induced upon activation of leukocytes transported in the nuclear compartment and activation of leukocytes
    Other phosphorylated at the serine and threonine residues upon cellular activation
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS