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FLASH GENE
Symbol GTPBP1 contributors: mct/npt - updated : 16-04-2008
HGNC name GTP binding protein 1
HGNC id 4669
Location 22q12-q13.1      Physical location : 39.101.806 - 39.129.590
Synonym name G-protein 1
Synonym symbol(s) GP-1, GP1, HSPC018, MGC20
DNA
TYPE functioning gene
STRUCTURE 27.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
Physical map
KCNJ4 22q13.1 potassium inwardly-rectifying channel, subfamily J, member 4 KDELR3 22q13.1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 DDX17 22q13.1 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 DMC1 22q13.1 DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast) LOC388900 22 LOC388900 TOMM22 22q12-q13 translocase of outer mitochondrial membrane 22 homolog (yeast) C22orf2 22q12 chromosome 22 open reading frame 2 KIAA0063 22q13.1 chromosome 22 open reading frame 2 GTPBP1 22q13.1 GTP binding protein 1 UNC84B 22q13.1-q13.3 unc-84 homolog B (C. elegans) DNAL4 22q13.1 dynein, axonemal, light polypeptide 4 LOC388901 22 LOC388901 NPTXR 22q13.1 neuronal pentraxin receptor CBX6 22q13.1 chromobox homolog 6 APOBEC3A 22q13.1-q13.2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A APOBEC3B 22q12-q13 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
12 - 5074 72.5 669 - Olsen (2006)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
Lymphoid/Immunelymph node   highly
Visualeye   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularsmooth  highly
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immunemacrophage
Nervousneuron
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • bearing GTP-binding motifs
  • HOMOLOGY
    interspecies homolog to murine GP-1
    homolog to C.elegans AGP-1,CGP-1
    Homologene
    FAMILY
  • G protein family
  • peptidyl-elongation factors
  • CATEGORY signaling , receptor membrane G
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • encoding a putative GTPase structurally related to peptidyl elongation factors
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by by interferon-gamma
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS