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FLASH GENE
Symbol GTPBP1 contributors: mct/npt - updated : 16-04-2008
HGNC name GTP binding protein 1
HGNC id 4669
Location 22q12-q13.1      Physical location : 39.101.806 - 39.129.590
Synonym name G-protein 1
Synonym symbol(s) GP-1, GP1, HSPC018, MGC20
DNA
TYPE functioning gene
STRUCTURE 27.00 kb     12 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status confirmed
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
12 - 5074 72.5 669 - Olsen (2006)
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveesophagus   highly
Lymphoid/Immunelymph node   highly
Visualeye   highly
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularsmooth  highly
cells
SystemCellPubmedSpeciesStageRna symbol
Lymphoid/Immunemacrophage
Nervousneuron
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • bearing GTP-binding motifs
  • HOMOLOGY
    interspecies homolog to murine GP-1
    homolog to C.elegans AGP-1,CGP-1
    Homologene
    FAMILY
  • G protein family
  • peptidyl-elongation factors
  • CATEGORY signaling , receptor membrane G
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • encoding a putative GTPase structurally related to peptidyl elongation factors
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    activated by by interferon-gamma
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS