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FLASH GENE
Symbol GSTZ1 contributors: npt/ - updated : 05-10-2005
HGNC name glutathione transferase zeta 1
HGNC id 4643
Location 14q24.3      Physical location : 77.787.229 - 77.797.939
Synonym name
  • S-(hydroxyalkyl)glutathione lyase
  • glutathione S-aryltransferase
  • glutathione transferase zeta 1 (maleylacetoacetate isomerase)
  • maleylacetoacetate isomerase
  • Synonym symbol(s) MAI, MAAI, GSTZ1-1, MGC2029
    EC.number 2.5.1.18, 5.2.1.2
    DNA
    TYPE functioning gene
    STRUCTURE 10.59 kb     9 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1395 24 216 - -
    - - 1269 19.2 174 - -
    - - 1485 17.7 161 - -
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    mono polymer dimer
    HOMOLOGY
    Homologene
    FAMILY
  • GST superfamily
  • zeta family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • glutathione-S-transferase
  • possessing glutathione peroxydase activity toward t-butyl and cumene hyperoxydes
  • possessing maleylacetoacetate isomerase activity
  • fundamental to the catabolism of aromatic AAs
  • last enzyme from the phenylalanine and tyrosine catabolic pathway
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS