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FLASH GENE
Symbol GSDMB contributors: SGE - updated : 04-06-2007
HGNC name gasdermin B
HGNC id 23690
Location 17q12      Physical location : 38.060.849 - 38.074.903
Synonym name
  • gasdermin-like
  • hypothetical protein PRO2521
  • Synonym symbol(s) PRO2521, PP4052,GSDML
    DNA
    TYPE functioning gene
    STRUCTURE 12.00 kb     8 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - 1578 - 403 - Suzuki
    - - 1646 - 394 - Suzuki
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveintestinelarge intestinecolon highly
     liver    
    Endocrinethyroid   highly
    Lymphoid/Immunethymus   highly
    Nervousbrain    
    Reproductivemale systemprostate   
    Respiratorylung    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow   
    cell lineage expressed in proliferating cells
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory , protooncogene
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • involved in the regulation of cell growth and differentiation in the skin and/or hair follicle epithelium, as well as the epithelium of the gastrointestinal tract
  • may be an oncogene (Saeki, 2009)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS