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FLASH GENE
Symbol GRPEL1 contributors: - updated : 12-01-2005
HGNC name GrpE-like 1, mitochondrial (E. coli)
HGNC id 19696
Location 4p16      Physical location : 7.061.779 - 7.069.800
Synonym name GrpE-like protein cochaperone
Synonym symbol(s) HMGE, FLJ25609
DNA
TYPE functioning gene
STRUCTURE 8.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
HSA250839 4p16.2 gene for serine/threonine protein kinase C4orf6 4p16 chromosome 4 open reading frame 6 EVC2 4p16.2-p16.1 Ellis van Creveld syndrome 2 (limbin) EVC 4p16 Ellis van Creveld syndrome CRMP1 4p16.1-p15 collapsin response mediator protein 1 LOC389197 4 hypothetical gene supported by BX648674 FLJ31564 LOC389198 4 LOC389198 WFS1 4p16.1 Wolfram syndrome 1 (wolframin) PPP2R2C 4p16.1 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform KIAA0935 4p16.1 protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform PGR1 4p16.1 T-cell activation protein LOC93622 4p16.1 hypothetical protein BC006130 S100P 4p16 S100 calcium binding protein P MGC9651 4p16.1 hypothetical protein MGC9651 CNO 4p16.1 cappuccino KIAA0232 4p16.1 KIAA0232 gene product KIAA1322 FLJ90575 4p16.1 hypothetical protein FLJ90575 MGC21874 4p16.1 transcriptional adaptor 2 (ADA2 homolog, yeast)-beta GRPEL1 4p16 GrpE-like 1, mitochondrial (E. coli) SORCS2 4p16 GrpE-like 1, mitochondrial (E. coli) AFAP 4p16 actin filament associated protein MGC10981 4p16.1 hypothetical protein MGC10981 LOC389199 4 hypothetical gene supported by BC031673 ABLIM2 4p16-p15 actin binding LIM protein 2 LOC391618 4 hypothetical gene supported by NM_003875 FLJ20356 HTRA3 4p16.1 serine protease HTRA3 ACOX3 4p15.3 acyl-Coenzyme A oxidase 3, pristanoyl FLJ35725 4p16.1 hypothetical protein FLJ35725 FLJ12891 4p16.1 hypothetical protein FLJ12891 GPR78 4p16.1 G protein-coupled receptor 78 CPZ 4p16 carboxypeptidase Z LOC391619 4 similar to ubiquitin-specific protease 17-like protein LOC391620 4 similar to ubiquitin-specific protease 17-like protein LOC391621 4 similar to ubiquitin-specific protease 17-like protein LOC391622 4 similar to ubiquitin-specific protease 17-like protein LOC391623 4 similar to ubiquitin-specific protease 17-like protein
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer aggregate
HOMOLOGY
interspecies ortholog to murine Grpel1
Homologene
FAMILY grpE family
CATEGORY chaperone/stress
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
basic FUNCTION essential fo the activities of the Hsp 70 system which assists protein folding
CELLULAR PROCESS protein, post translation, folding
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
  • forming a dimer with DnaK
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS