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FLASH GENE
Symbol GRM4 contributors: npt/ - updated : 30-11-2005
HGNC name glutamate receptor, metabotropic 4
HGNC id 4596
Location 6p21.3      Physical location : 33.989.628 - 34.101.443
Synonym name glutamate metabotropic receptor 4
Synonym symbol(s) MGLUR4, GPRC1D, mGlu4
DNA
TYPE functioning gene
STRUCTURE 111.82 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
HKE2 6p21.3 HLA class II region expressed gene KE2 RAB2L 6p21.3 RAB2, member RAS oncogene family-like TAPBP 6p21.3 TAP binding protein (tapasin) ZNF297 6p21.3 zinc finger protein 297 DAXX 6p21.3 death-associated protein 6 LOC346177 6p21.31 similar to myosin:SUBUNIT=regulatory light chain LYPLA2P1 6p21.31 lysophospholipase II pseudogene 1 KIFC1 6p21.3 kinesin family member C1 PHF1 6p21.3 PHD finger protein 1 C6orf82 6pter-p21.31 chromosome 6 open reading frame 82 MGC23166 BAK1 6p21.3 BCL2-antagonist/killer 1 ITPR3 6p21 inositol 1,4,5-triphosphate receptor, type 3 C6orf125 6p21.31 chromosome 6 open reading frame 125 IHPK3 6p2131-p21.2 inositol hexaphosphate kinase 3 LEMD2 6p21.31 LEM domain containing 2 MLN 6p21.3 motilin GRM4 6p21.3 glutamate receptor, metabotropic 4 LOC389381 6 LOC389381 LOC391914 6 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) CYCSL1 6p21.31 cytochrome c, somatic-like 1 HMGA1 6p21.3 high mobility group AT-hook 1 MGC57858 6p21.31 hypothetical protein MGC57858 LOC391915 6 hypothetical gene supported by U12465; NM_007209 NUDT3 6p21.2 nudix (nucleoside diphosphate linked moiety X)-type motif 3 RPS10 6p21.3 ribosomal protein S10 PACSIN1 6p21.3 protein kinase C and casein kinase substrate in neurons 1 SPDEF 6p21.3 SAM pointed domain containing ets transcription factor C6orf106 6p21.31 chromosome 6 open reading frame 106 MGC4614 6p21.31 hypothetical protein MGC4614
regionally located within a susceptibility locus for juvenile myoclonic epilepsy
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
10 - 3884 98.2 912 - -
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrainhindbraincerebellum highly
 braindiencephalonthalamus lowly
 braindiencephalonhypothalamus lowly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to C.elegans y4c6a.2
Homologene
FAMILY
  • G-protein coupled receptor 3 family
  • CATEGORY signaling neurotransmitter , receptor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • major excitatory neurotransmitter in the central nervous system
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • PRKCABP
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS