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FLASH GENE
Symbol GRK7 contributors: - updated : 21-07-2005
HGNC name G protein-coupled receptor kinase 7
HGNC id 17031
Location 3q21-q24      Physical location : 141.497.042 - 141.535.890
Synonym symbol(s) GPRK7
EC.number 2.7.1-
DNA
TYPE functioning gene
STRUCTURE 10.00 kb     4 Exon(s)
MAPPING cloned Y linked Y status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialbarrier liningretinal pigment epithelium (RPE)  
cells
SystemCellPubmedSpeciesStageRna symbol
Visualcone photoreceptor
Visualrod photoreceptor
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
two RGS domains
HOMOLOGY
Homologene
FAMILY
  • SER/THR family of protein kinases
  • GPRK subfamily
  • CATEGORY signaling , receptor membrane G
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • phosphorylating cone opsins there by initiating their deactivation
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS