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FLASH GENE
Symbol GRIP2 contributors: mct - updated : 22-04-2011
HGNC name glutamate receptor interacting protein 2
HGNC id 23841
Location 3p25.1      Physical location : 14.530.618 - 14.583.588
Synonym name GRIP2 protein
Synonym symbol(s) KIAA1719
DNA
TYPE functioning gene
STRUCTURE 52.97 kb     25 Exon(s)
MAPPING cloned N linked N status provisional
Physical map
FLJ11036 3p25.2 hypothetical protein FLJ11036 LOC344866 3p25.2 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) TIP120B 3p25.2-p24.2 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) RPL32 3p25-p24 ribosomal protein L32 LOC391512 3 similar to WD repeat domain 10 isoform 3 LOC391513 3 similar to ENSANGP00000014786 LOC391514 3 similar to MAP/microtubule affinity-regulating kinase 1 LOC389096 3 similar to nucleoporin 210; nuclear pore membrane glycoprotein 210; gp210 KIAA0763 3p25.1 similar to nucleoporin 210; nuclear pore membrane glycoprotein 210; gp210 NUP210 3p25.2-p25.1 nucleoporin 210 HDAC11 3p25.1 histone deacetylase 11 FBLN2 3p25-p24 fibulin 2 WNT7A 3p25 wingless-type MMTV integration site family, member 7A FLJ35107 3p25.1 hypothetical protein FLJ35107 LOC391515 3 similar to putative pheromone receptor gV1R1 FLJ31709 MGC3222 3p25.1 hypothetical protein MGC3222 XPC 3p25.1 xeroderma pigmentosum, complementation group C LSM3 3p25.1 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) SLC6A6 3p25-p24 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 GRIP2 3p24-p23 glutamate receptor interacting protein 2 LOC131973 3p25.1 similar to rhomboid family 1; epidermal growth factor receptor, related sequence LOC51244 3p25.1 hypothetical protein LOC51244 DKFZP434N1817 3p25.1 hypothetical protein DKFZp434N1817 FGD5 3p25.1 FYVE, RhoGEF and PH domain containing 5 NR2C2 3p25 nuclear receptor subfamily 2, group C, member 2 MRPS25 3p25 mitochondrial ribosomal protein S25 ZFYVE20 3p25.1 zinc finger, FYVE domain containing 20 LOC344875 3p25.1 similar to RIKEN cDNA E330026B02 CAPN7 3p24 calpain 7 SH3BP5 1q43 SH3-domain binding protein 5 (BTK-associated) LOC389097 3 similar to Nonhistone chromosomal protein HMG-17 (High-mobility group nucleosome binding domain 2) MGC24132 3p25.1 hypothetical protein MGC24132 EAF1 3q25.1 ELL associated factor 1 COLQ 3p24.2 collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase HPCL2 3p25.1 2-hydroxyphytanoyl-CoA lyase BTD 3p25 biotinidase KIAA0379 3p25.2-p24.2 biotinidase LOC131961 3p25.1 similar to inosine monophosphate dehydrogenase 1 isoform a; sWSS2608 GALNT7 4q31.1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7) MGC15763 3p25-p24 hypothetical protein BC008322 RAFTLIN 3p25.1 raft-linking protein
RNA
TRANSCRIPTS type
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
25 - 7977 - 1140 - 2000 11214971
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION     plasma membrane
    intracellular
intracellular,cytoplasm,cytosolic
basic FUNCTION
  • may serve to organize macromolecular complexes, linking AMPA-Rs and other membrane proteins to the cytoskeleton and membrane trafficking and signal transduction pathways
  • multi-PDZ domain-containing protein that interact with the C-termini of AMPA-R GRIA2 and GRIA3 subunits
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein bind to the C-termini of AMPA-R GRIA2 and GRIA3 subunits
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS