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FLASH GENE
Symbol GREB1L contributors: mct - updated : 09-01-2018
HGNC name growth regulation by estrogen in breast cancer-like
HGNC id 31042
Corresponding disease
RADP3 renal adysplasia 3
Location 18q11.1      Physical location : 18.822.202 - 19.102.789
Synonym name
  • KIAA1772
  • hypothetical protein FLJ13687
  • GREB1-like protein
    • Synonym symbol(s) FLJ13687, C18orf6, KIAA1772, RHDA3
    DNA
    TYPE functioning gene
    STRUCTURE 254.46 kb     20 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    20 - 6052 214 1923 - 2017 29100090
    EXPRESSION
    Type
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Reproductivefemale systemuteruscervix   Mus musculusFetal
     female systemvagina    Mus musculusFetal
     male systemmale genital tractepididymis   Mus musculusFetal
    Urinarybladder     Mus musculusFetal
     kidney     Mus musculusFetal
     ureter     Mus musculusFetal
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • GREB1 family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • role for GREB1L in renal morphogenesis
  • plays a major role in early metanephros and genital development
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • target of retinoic acid signaling, a pathway that is crucial for renal development and the dysregulation of which has been proposed as a causative mechanism for urinary tract malformations
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) RADP3
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS