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FLASH GENE
Symbol GPX6 contributors: - updated : 04-08-2005
HGNC name glutathione peroxidase 6 (olfactory)
HGNC id 4558
Location 6p22.1      Physical location : 28.471.072 - 28.483.570
EC.number 1.11.1.9
DNA
TYPE functioning gene
STRUCTURE 12.00 kb     5 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
LOC391888 6 similar to dJ408B20.3 (novel protein similar to 60S acidic ribosomal protein P2 (RPLP2)) LOC391889 6 similar to olfactory receptor MOR256-8 LOC340192 6p21.33 similar to Hypothetical protein KIAA0036 LOC391890 6 similar to olfactory receptor MOR256-13 LOC391891 6 similar to olfactory receptor GA_x6K02T2QHY8-11688984-11689964 LOC391892 6 similar to Olfactory receptor 2B8 (Hs6M1-29P) LOC391893 6 similar to Olfactory receptor 1F12 (Hs6M1-35P) ZNF165 6p21.3 zinc finger protein 165 LOC391894 6 similar to Zinc finger protein 192 (LD5-1) ZNF435 6p21.33 zinc finger protein 435 ZNF192 6p21.3 zinc finger protein 192 LOC222701 6p21.33 similar to Zinc finger protein 192 (LD5-1) LOC391895 6 similar to hypothetical protein MGC42493 ZNF193 6p21..3 zinc finger protein 193 P1P373C6 C6orf194 6p21.33 chromosome 6 open reading frame 194 ZNF187 6p21.31 zinc finger protein 187 PGBD1 6p21.31 piggyBac transposable element derived 1 ZNF323 6p zinc finger protein 323 ZNF306 6p21.33 zinc finger protein 306 ZNF305 6p21.3 zinc finger protein 305 LOC391896 6 similar to Zinc finger protein 354A (Transcription factor 17) (Zinc finger protein eZNF) ZNF453 6p21.33 zinc finger protein 453 COX11P 6p23-p22 COX11 homolog, cytochrome c oxidase assembly protein (yeast) pseudogene TRLP1 6p25-q13 tRNA leucine (AAG) pseudogene 1 TRMEP1 6p25-q13 tRNA methionine elongator pseudogene 1 GPX6 6p21.33 glutathione peroxidase 6 (olfactory) GPX5 6p21.32 glutathione peroxidase 5 (epididymal androgen-related protein) ZNF452 6p21.33 zinc finger protein 452 LOC282925 6p21.33 similar to 33 kDa protein LOC222693 6p21.33 similar to dJ207F6.1 (novel nucleolar protein NOP56 like protein) LOC391897 6 similar to ribosomal protein L13; 60S ribosomal protein L13; breast basic conserved protein 1 RFP 6p21.3 ret finger protein
RNA
TRANSCRIPTS type messenger
EXPRESSION
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , tetramer
isoforms Precursor
HOMOLOGY
interspecies ortholog to murine Gpx6
Homologene
FAMILY glutathione peroxidase family
CATEGORY enzyme , secretory
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • protecting cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS