basic FUNCTION
| involved in free radical detoxification and reduction of hydrogen peroxide |
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catalyzing the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione |
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functioning in the protection of cells against oxidative damage |
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having potent extracellular antioxidant activity |
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major antioxidative enzyme that was induced upon nontoxic proteasome inhibition in endothelial cells |
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borderline defense mechanism of endothelial cell-derived GPx-3 to protect the vasculature from oxidative stress |
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GPX5 protein, and the epithelial proteins GPX1, GPX3, and cellular GPX4, all functioning in the mammalian epididymis at different stages of the sperm epididymal journey, and in different epididymis compartments |
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from the blood binds to basement membranes of specific epithelial cells and the cells modify their basement membranes to cause the binding |
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importance of this plasma antioxidant enzyme in regulating platelet activity, endothelial function, platelet-dependent thrombosis, and vascular thrombotic propensity |
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plasma antioxidant enzyme, maintaining genomic integrity by inactivating reactive oxygen species (ROS), known DNA-damaging agents and mediators of cancer chemotherapy response |
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new retinoid target gene, crucial for human skeletal muscle precursor cell survival |
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plays a main role in removing hydro- and lipoperoxides from the body |
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has an important function of scavenging hydrogen peroxide and preventing cancer |