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Symbol GPSM3 contributors: - updated : 24-02-2006
HGNC name G-protein signaling modulator 3 (AGS3-like, C. elegans)
HGNC id 13945
Location 6p21.3      Physical location : 3.419.561 - 32.163.300
Synonym name
  • chromosome 6 open reading frame 9
  • activator of G-protein signaling 4
  • Synonym symbol(s) G18, NG1, G18.2, G18.1A, G18.1B, C6orf9, AGS4
    DNA
    TYPE functioning gene
    STRUCTURE 4.00 kb     8 Exon(s)
    regulatory sequence cytosine-phosphate-guanine/HTF
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   highly
    Lymphoid/Immunelymph node   highly
     spleen   highly
     thymus   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • three G-protein regulatory motifs downstream of an amino terminus domain with multiple prolines
  • HOMOLOGY
    interspecies homolog to murine Gpsm3
    Homologene
    FAMILY
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • having GTPase activator activity
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS