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FLASH GENE
Symbol GPRIN2 contributors: mct - updated : 28-08-2014
HGNC name G protein regulated inducer of neurite outgrowth 2
HGNC id 23730
Location 10q11.22      Physical location : 46.993.545 - 47.000.567
Synonym name KIAA0514 gene product
Synonym symbol(s) MGC15171, KIAA0514, GRIN2, IP6
DNA
TYPE functioning gene
STRUCTURE 8.15 kb     3 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 1823 47 458 - 2004 15488195
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousbrain    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY unknown/unspecified
SUBCELLULAR LOCALIZATION
basic FUNCTION unknown
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
  • can bind to the GTP-bound form of GNAO1
  • CSNK2A1 activity is inhibited by NOLC1 and reactivated by GPRIN2 by competitive binding at the substrate recognition site of CSNK2A1
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS