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FLASH GENE
Symbol GPRC5D contributors: npt/ - updated : 13-07-2007
HGNC name G protein-coupled receptor, family C, group 5, member D
HGNC id 13310
Location 12p13.1      Physical location : 13.093.710 - 13.103.318
Synonym name
  • metabotropic glutamate receptor-like
  • orphan G-protein coupled receptor
    • Synonym symbol(s) MGC129714, MGC129713
    DNA
    TYPE functioning gene
    SPECIAL FEATURE opposite orientation
    text in opposite orientation with RAI3
    STRUCTURE 9.61 kb     3 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status confirmed
    Physical map
    BCLG 12p13-p12 glutamate receptor, ionotropic, N-methyl D-aspartate 2B LOC387839 12 similar to prothymosin alpha LRP6 12p11.2-p13.3 low density lipoprotein receptor-related protein 6 MORF4LP4 4q1.2 mortality factor 4 like pseudogene 4 FLJ10298 12p13.2 hypothetical protein FLJ10298 LOH12CR1 12p12 loss of heterozygosity, 12, chromosomal region 1 LOC387840 12 LOC387840 DUSP16 12p13-p12 dual specificity phosphatase 16 LOC390296 12 similar to hypothetical protein CREBL2 12p13.2-p13.1 cAMP responsive element binding protein-like 2 GPR19 12p12.3 G protein-coupled receptor 19 CDKN1B 12p13.1-p12 cyclin-dependent kinase inhibitor 1B (p27, Kip1) DKFZP434F0318 12p13.2 hypothetical protein DKFZp434F0318 DDX47 12p13.2 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 LOC341465 12p13.2 similar to 40S ribosomal protein S6 (Phosphoprotein NP33) LOC387841 12 similar to ribosomal protein L13a; 60S ribosomal protein L13a; 23 kD highly basic protein RAI3 12p13-p12.3 retinoic acid induced 3 GPRC5D 12p13.3 G protein-coupled receptor, family C, group 5, member D HEBP1 12p13.2 heme binding protein 1 LOC387842 12 similar to 5-hydroxytryptamine receptor 7 isoform a; serotonin 5-HT-7 receptor KIAA1467 12p13.2 KIAA1467 protein GSG1 12p13.31 germ cell associated 1 EMP1 12p12.3 epithelial membrane protein 1 FLJ33810 12p13.2 hypothetical protein FLJ33810 GRIN2B 12p12 glutamate receptor, ionotropic, N-methyl D-aspartate 2B
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    3 - 1038 - 345 - -
    EXPRESSION
    Type restricted
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Skin/Tegumentskin   specific
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • seven transmembrane segments (7TM)
  • short aminoterminal domain of some 30-50 AA
    • HOMOLOGY
    interspecies homolog to murine Gprc5d (82.6 pc)
    Homologene
    FAMILY
  • G-protein coupled receptor 3 family
    • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • acting as a metabotropic glutamate, GABA-B-like receptor
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction , sensory transduction/vision
    visual perception
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS