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FLASH GENE

Symbol

GPRASP1

contributors: - updated : 23-09-2005

HGNC name	G protein-coupled receptor-associated sorting protein
HGNC id	24834

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	Xq22.1      Physical location : 101.906.293 - 101.914.008
Synonym symbol(s)	KIAA0443, GASP, GASP1, FLJ12969, FLJ13382

DNA

TYPE	functioning gene
STRUCTURE	7.00 kb     5 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous brain basal nuclei caudate nucleus       brain diencephalon amygdala     Reproductive female system ovary       Urinary kidney         Visual eye retina fovea       eye retina macula       eye anterior segment iris

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies

ortholog to murine Gprasp1

Homologene

FAMILY

CATEGORY

receptor membrane G

SUBCELLULAR LOCALIZATION	plasma membrane
	intracellular
	intracellular,nucleus

basic FUNCTION	may represent an important protein family regulating GPCR physiology
	modulating lysosomal sorting and functional down-regulation of a variety of G protein-coupled receptors

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS