Selected-GenAtlas references SOURCE GeneCards NCBI Gene Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GPR89B contributors: mct/npt - updated : 14/11/2008
HGNC name G protein-coupled receptor 89B
HGNC id 13840
Location 1q21.1      Physical location : 147.400.505 - 147.465.747
Synonym name
  • Golgi pH regulator
  • G protein-coupled receptor 89
  • Synonym symbol(s) GPHR, GPR89, SH120
    DNA
    TYPE functioning gene
    STRUCTURE 65.25 kb     14 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    14 - 2150 - 455 - Gregory (2006)
    EXPRESSION
    Type widely
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestiveesophagus   highly
    Endocrineadrenal gland   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    HOMOLOGY
    Homologene
    FAMILY
    CATEGORY regulatory , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
        intracellular
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,organelle,Golgi
    basic FUNCTION
  • exhibited a voltage-dependent anion-channel activity that may function in counterion conductance
  • modulates Golgi functions through regulation of acidification
  • functions as an anion channel
  • crucial role for facilitating sufficient luminal acidification for normal Golgi functions
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS