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FLASH GENE
Symbol GPR19 contributors: - updated : 05-07-2006
HGNC name G protein-coupled receptor 19
HGNC id 4473
Location 12p12.3      Physical location : 12.813.994 - 12.849.121
DNA
TYPE anonymous DNA segment
STRUCTURE 35.00 kb     2 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
Map pter - ETV6 - CDKN1B - GPR19 -cen
Authors Montpetit (99)
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland    
Hearing/Equilibriumear    
Lymphoid/Immunelymph node    
Nervousbrainbasal nucleicaudate nucleus  
nervousbrainbasal nucleiputamen  
Nervousbraindiencephalonthalamus  
Reproductivemale systemtestis   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor
HOMOLOGY
intraspecies homolog to D2 dopamine and adregenic receptors,strongly
Homologene
FAMILY G protein coupled receptor family
CATEGORY receptor
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION may be target of genetic alterations found in several cancers
CELLULAR PROCESS
PHYSIOLOGICAL PROCESS
PATHWAY
metabolism
signaling
a component
INTERACTION
DNA
RNA
small molecule
protein
cell & other
REGULATION
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral   deletion    
in childhood acute lymphoblastic leukemia (ALL)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS