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FLASH GENE
Symbol GPR155 contributors: mct - updated : 03-11-2010
HGNC name G protein-coupled receptor 155
HGNC id 22951
Location 2q31.1      Physical location : 175.296.375 - 175.351.811
Synonym name G-protein coupled receptor PGR22
Synonym symbol(s) DEP.7, PGR22, DEPDC3, FLJ31819, FLJ31819, FLJ39346
DNA
TYPE functioning gene
STRUCTURE 55.53 kb     16 Exon(s)
MAPPING cloned Y linked N status provisional
Physical map
ZAK 2q24.2 similar to Homeobox even-skipped homolog protein 2 (EVX-2) LOC391461 2 similar to ribosomal protein S2; 40S ribosomal protein S2 CDCA7 2q31 cell division cycle associated 7 LOC344178 2q31.1 similar to peptidylprolyl isomerase A (cyclophilin A) LOC344181 2q31.1 similar to ribosomal protein L5; 60S ribosomal protein L5 SP3 2q31 Sp3 transcription factor LOC389061 2 LOC389061 LOC389062 2 LOC389062 LOC391462 2 similar to protein 40kD PTD004 2q31.1 hypothetical protein PTD004 LOC391463 2 similar to Leucine-rich repeat-containing protein 2 LOC389063 2 similar to Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing protein) (Single-strand binding protein) (hnRNP core protein A1) (HDP-1) (Topoisomerase-inhibitor suppressed) LOC389064 2 hypothetical gene supported by AK128215 CIR 2q31.1 CBF1 interacting corepressor SES3 2q31.1 secernin 3 GPR155 2q31.1 G protein-coupled receptor 155 WASPIP 2q31.1 Wiskott-Aldrich syndrome protein interacting protein LOC151561 2q31.2 similar to H3 histone, family 3B CHRNA1 2q31-q32 cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) CHN1 2q31-q32.1 chimerin (chimaerin) 1 ATF2 2q32 activating transcription factor 2 ATP5G3 2q31.1 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c (subunit 9) isoform 3 LOC391464 2 similar to 40S ribosomal protein S15a KIAA1715 2q31 KIAA1715 LOC344191 2q31.2 similar to Homeobox even-skipped homolog protein 2 (EVX-2)
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
16 - 7324 96.9 870 - 2003 12679517
17 - 7473 96.9 870 - 2003 12679517
EXPRESSION
Type widely
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Hearing/Equilibriumearinnercochlea highly
Nervousbrainbasal nucleistriatum highly
 brainlimbic systemhippocampus highly
 nerve   highly
Respiratoryrespiratory tracttrachea  highly
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Nervousperipherous   
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
interspecies homolog to murine Gpr155 (89 p100)
Homologene
FAMILY
CATEGORY receptor membrane G
SUBCELLULAR LOCALIZATION     plasma membrane
text integral membrane protein
basic FUNCTION
  • involved in intracellular signaling cascade
  • might also play a role in sensory information processing and memory
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to autism
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS