Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol GPR137B contributors: - updated : 22-06-2006
HGNC name G protein-coupled receptor 137B
HGNC id 11862
Location 1q42-q43      Physical location : 236.305.831 - 236.372.208
Synonym name transmembrane 7 superfamily member 1 (upregulated in kidney)
Synonym symbol(s) TM7SF1
DNA
TYPE functioning gene
STRUCTURE 66.00 kb     7 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
text with two minor alternatively spliced isoforms
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 2400 45.6 399 - Spangenberg
  • an open reading frame of 1998 nucleotides
  • seven predicted transmembrane domains, a potential Asn-linked glycosylation site in its predicted extracellular N-terminal region, several potential serine/threonine phosphorylation sites and a potential tyrosine phosphorylation site in its C-terminal tail
  • its genbank sequence gives a length of 1998bp
  • - splicing 2300 - 328 - Spangenberg
    seven transmembrane domain protein with a truncated C-terminal domain
    - splicing 2200 - - - Spangenberg
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart    
    Hearing/Equilibriumear    
    Nervousbrain    
    Reproductivefemale systemplacenta   
    Respiratorylung    
    Skin/Tegumentskin    
    Urinarykidney    
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    seven transmembrane segments (7TM) receptor
    conjugated GlycoP
    HOMOLOGY
    interspecies homolog to murine Gpr137b (94.5pc)
    intraspecies homolog to GPCR class of transmembrane proteins
    Homologene
    FAMILY
  • putative seven pass transmembrane superfamily
  • putative G protein coupled receptor superfamily
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other upregulated during kidney development
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS