basic FUNCTION
| high-affinity receptor for lysophosphatidylcholine (LPC), a major phospholipid component of oxidized low density lipoprotein |
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activating a G alpha protein, most likely G alpha(q) |
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may be involved in apoptosis |
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might have a biological role in diverse pathological conditions including atherosclerosis |
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stress-inducible G protein-coupled receptor that is expressed on several cell types within atherosclerotic lesions |
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G protein-coupled receptor that can be induced by various stressors |
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functioning at the G2/M checkpoint to delay mitosis |
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may serve as a mechanism for T- and B-cells, and other cell types, to slow their proliferation and repair damaged DNA to ensure proper replication |
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GPR132-signaling serves to dampen intestinal inflammation via the production of IFNG1, which, in turn, enhances monocyte maturation to a less inflammatory program and ultimately reduces eosinophil-induced injury of colonic tissues |
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GPR132 is a potential modulator of the cell cycle in IKZF1-deleted B-acute lymphoblastic leukemia (ALL) |
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GPR4, GPR68, GPR65, GPR132 are regulators of cell proliferation and migration during tumor growth and wound healing |