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FLASH GENE

Symbol

GPR123

contributors: - updated : 27-03-2007

HGNC name	G protein-coupled receptor 123
HGNC id	13838

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	10q26      Physical location : 134.901.408 - 134.945.178
Synonym symbol(s)	KIAA1828

DNA

TYPE	functioning gene
STRUCTURE	58.00 kb     16 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed Variant 1 - splicing 6004 Variant 1 137 1280 - - Variant 2 - splicing - Variant 2 - - - Bjarnadóttir coding for a non-fonctional product Variant 3 - splicing - Variant 3 - - - Bjarnadóttir shorter N-ter

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine large intestine colon     Nervous brain         Urinary kidney         Visual eye

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective bone

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

a seven transmembrane domain (7tm_2)

HOMOLOGY

interspecies	homolog to rattus Gpr123 (74.26 pc)
	homolog to murine Gpr123 (82.85 pc)

Homologene

FAMILY	G-protein coupled receptor 2 family
	LN-TM7 subfamily

CATEGORY

receptor membrane G

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

unknown

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

signal transduction

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS