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FLASH GENE
Symbol GPR113 contributors: - updated : 26-03-2007
HGNC name G protein-coupled receptor 113
HGNC id 18989
Location 2p24.1      Physical location : 26.531.040 - 26.569.685
Synonym name G protein-coupled receptor PGR23
Synonym symbol(s) hGPCR37, PGR23
DNA
TYPE functioning gene
STRUCTURE 9.00 kb     13 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- splicing 3240 116 1079 - -
- splicing - - - - Bjarnadóttir
  • having a frame shift
  • coding for a non-fonctional product
  • - splicing - - - - Bjarnadóttir
  • laking exons 1, 2, 5 & 6
  • fonctional product
  • EXPRESSION
    Type widely
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Cardiovascularheart   moderately
    Gustatory (taste)tonguecircumvallate papillae   
    Lymphoid/Immunelymph node   highly
     thymus   lowly
    Nervousbrain   lowly
    Reproductivemale systemtestis  moderately
    Urinarykidney   lowly
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / hematopoieticbone marrow  highly
    Epithelialsensorygustatory  
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • N-terminal extracellular domain with two functional domains
  • a peptide hormone-binding domain (HormR)
  • a G-protein-coupled receptor proteolytic site (GPS)
  • a seven transmembrane region (7tm_2)
  • HOMOLOGY
    Homologene
    FAMILY
  • G-protein coupled receptor 2 family
  • LN-TM7 subfamily
  • CATEGORY receptor membrane G
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • may be involved in neuropeptide signaling pathway
  • may function to recognize one of the known neuropeptides that are associated with taste buds
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling signal transduction
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS