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FLASH GENE
Symbol GPC2 contributors: - updated : 11-04-2006
HGNC name glypican 2 (cerebroglycan)
HGNC id 4450
Location 7q22.1      Physical location : 99.767.229 - 99.774.990
Synonym symbol(s) FLJ38962, DKFZp547M109
DNA
TYPE functioning gene
STRUCTURE 7.00 kb     10 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked N status provisional
Physical map
CYP3A7 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 7 CYP3A5P2 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 5 pseudogene 2 CYP3A4 7q21.3-q22.1 cytochrome P450, family 3, subfamily A, polypeptide 4 CYP3A43 7q21.1 cytochrome P450, family 3, subfamily A, polypeptide 43 TRIM4 7q22-q31.1 tripartite motif-containing 4 AZGP1 7q22.1 alpha-2-glycoprotein 1, zinc LOC392078 7 hypothetical gene supported by BC022382 ZNF36 7q21.3-q22.1 zinc finger protein 36 (KOX 18) ZNF38 7q21-q22 zinc finger protein 38 ZNF3 7q22.1 zinc finger protein 3 (A8-51) COPS6 7q22.1 zinc finger protein 3 (A8-51) MCM7 7q21.3-q22.1 MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) AP4M1 7q22.1 adaptor-related protein complex 4, mu 1 subunit TAF6 7q11 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa MGC40499 7q22.1 hypothetical protein MGC40499 LOC255374 7q22.1 similar to hypothetical protein MGC49416 LOC392079 7 similar to ribosomal protein L7 LOC389541 7 similar to CG14977-PA FLJ10925 7q22.1 hypothetical protein FLJ10925 GAL3ST-4 7q22 hypothetical protein FLJ10925 GPC2 7q22.1 glypican 2 (cerebroglycan) STAG3 7q22 stromal antigen 3 GATS 7q22.1 opposite strand transcription unit to STAG3 LOC392080 7 similar to opposite strand transcription unit to Stag3; Gats protein PILRB 7q22.1 paired immunoglobin-like type 2 receptor beta PILRA 7q22 paired immunoglobin-like type 2 receptor alpha ZCWPW1 7q22.1 zinc finger, CW-type with PWWP domain 1 FLJ20257 7q22.1 hypothetical protein FLJ20257 MGC22793 7q22.1 hypothetical protein MGC22793 THG-1 7p21-p15 TSC-22-like FLJ37538 7q22.1 hypothetical protein FLJ37538
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type restricted
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineadrenal gland    
Lymphoid/Immunelymph node    
 thymus    
Nervousbrain    
Reproductivefemale systemuterus   
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text expressed specifically during neuronal differentiation
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a GPI anchor
conjugated LipoP
isoforms Precursor
HOMOLOGY
interspecies homolog to murine Gpc2
homolog to rattus Gpc2
Homologene
FAMILY glypican family
CATEGORY adhesion , chaperone/stress
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • cell surface proteoglycan bearing heparan sulfate
  • may have a function related to the motile behaviors of developing neurons
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS development
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS