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FLASH GENE
Symbol GPAT2 contributors: mct/npt - updated : 01-12-2009
HGNC name glycerol-3-phosphate acyltransferase 2, mitochondrial
HGNC id 27168
Location 2q11.2      Physical location : 96.687.694 - 96.700.727
EC.number 2.3.1.15
DNA
TYPE functioning gene
STRUCTURE 13.03 kb     22 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
21 - 2840 - 795 - Wang (2007)
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver    
Reproductivemale systemtestis  highly Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • GPAT/DAPAT family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria,inner
    intracellular,cytoplasm,organelle,membrane
    intracellular,cytoplasm,cytosolic,microsome
    basic FUNCTION
  • N-ethylmaleimide (NEM)-sensitive isoforms in microsomes and mitochondrialikely having a specialized function in testis (Wang 2007)
  • catalyzes the initial and rate-limiting step in glycerolipid synthesis (Wang 2007)
  • minor NEM-sensitive mitochondrial isoform (Gimeno 2008)
  • can play important roles in the development of hepatic steatosis, insulin resistance, and obesity (Gimeno 2008)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS