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FLASH GENE
Symbol GOLGA7 contributors: - updated : 28-05-2007
HGNC name golgi autoantigen, golgin subfamily a, 7
HGNC id 24876
Location 8p11.21      Physical location : 41.348.080 - 41.368.497
Synonym name Golgi complex-associated protein of 16kDa
Synonym symbol(s) GCP16, HSPC041, MGC4876, MGC21096, GOLGA3AP1
DNA
TYPE functioning gene
STRUCTURE 20.00 kb     6 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
- - 2042 - 137 - Jia
- - 1919 - 137 - Jia
six exons
EXPRESSION
Type ubiquitous
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Cardiovascularheart    
Endocrinethyroid   highly
Nervousbrain   highly
 nervecranial nerve  highly
Reproductivefemale systemuterus   
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Blood / hematopoieticbone marrow   
cell lineage
cell lines Ewing's sarcoma
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
a Golgi localization signal at the NH2-terminal region (positions 137-237)
HOMOLOGY
interspecies homolog to murine Golga7
Homologene
FAMILY golgin subfamily
CATEGORY antigen
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,membrane
intracellular,cytoplasm,organelle,Golgi
basic FUNCTION
  • acylated membrane protein, associated with GCP170, and possibly involved in vesicular transport from the Golgi to the cell surface
  • may have palmitoyltransferase activity in association with ZDHHC9
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component of a complex formed by ZDHHC9, ERF4 and GOLGA7
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacts with ZDHHC9 (constitute a protein fatty acyltransferase with specificity for H- and N-Ras)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS