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FLASH GENE
Symbol GNRH2 contributors: mct/npt - updated : 12-07-2008
HGNC name gonadotropin-releasing hormone 2
HGNC id 4420
Location 20p13      Physical location : 3.024.267 - 3.026.391
Synonym name
  • gonadoliberin 2
  • progonadoliberin II
  • luliberin II
  • luteinizing hormone-releasing hormone II
  • Synonym symbol(s) LHRH2, GON2, LH-RHII, GnRH-II
    DNA
    TYPE functioning gene
    STRUCTURE 2.00 kb     4 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked N status provisional
    Physical map
    NOL5A 20p13 nucleolar protein 5A (56kDa with KKE/D repeat) IDH3B 20p13 isocitrate dehydrogenase 3 (NAD+) beta KIAA1442 20p13 KIAA1442 protein RPL19P1 20p13 ribosomal protein L19 pseudogene 1 CPXM 20p12.3-p13 carboxypeptidase X (M14 family) C20orf141 20p13 chromosome 20 open reading frame 141 LOC388781 20 similar to RIKEN cDNA 4933425O20 C20orf81 20p13 chromosome 20 open reading frame 81 VPS16 20p13-p12 vacuolar protein sorting 16 (yeast) PTPRA 20p13 protein tyrosine phosphatase, receptor type, A GNRH2 20p13 gonadotropin-releasing hormone 2 MRPS26 20p13 mitochondrial ribosomal protein S26 OXT 20p13 oxytocin, prepro- (neurophysin I) AVP 20p13 arginine vasopressin (neurophysin II, antidiuretic hormone, diabetes insipidus, neurohypophyseal) UBCE7IP5 20p13 likely ortholog of mouse ubiquitin conjugating enzyme 7 interacting protein 5 FLJ13149 20p13 hypothetical protein FLJ13149 ProSAPiP1 20p13 ProSAPiP1 protein C20orf116 20p13 chromosome 20 open reading frame 116 ITPA 20p inosine triphosphatase (nucleoside triphosphate pyrophosphatase) SLC4A11 20p12 solute carrier family 4, sodium bicarbonate transporter-like, member 11 C20orf194 20p13 chromosome 20 open reading frame 194 UBE2V1P1 20p13 ubiquitin-conjugating enzyme E2 variant 1 pseudogene 1 ATRN 20p13 attractin
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    - - - - - midbrain -
    - - 423 12 120 - Darby (2007)
    - - 402 - 113 - Darby (2007)
    - - 399 - 112 - Darby (2007)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Nervousbrainmidbrain   
    Reproductivemale systemprostate   
    Visualeye    
    tissue
    SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
    Blood / Hematopoieticbone marrow   
    Connectivebone   
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to C.elegans f46f2.3
    Homologene
    FAMILY
  • GnRH family
  • CATEGORY signaling hormone
    SUBCELLULAR LOCALIZATION extracellular
    basic FUNCTION
  • gonadotropin releasing hormone
  • including a GNRH-associated peptide
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other regulated by the androgen receptor in prostate cancer
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in prostate cancer
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS