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FLASH GENE
Symbol GNPDA2 contributors: mct - updated : 28-08-2010
HGNC name glucosamine-6-phosphate deaminase 2
HGNC id 21526
Location 4p12      Physical location : 44.704.168 - 44.728.612
Synonym name
  • glucosamine-6-phosphate isomerase
  • GlcN6P deaminase 2
  • Synonym symbol(s) 4921523I18Rik, SB52, GNP2
    EC.number 3.5.99.6
    DNA
    TYPE functioning gene
    STRUCTURE 24.45 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 1939 - 276 - Arreola (2003)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrinepancreasislet of Langerhans   
    Nervousbraindiencephalonhypothalamus  
    Reproductivemale systemtestis   
    Urinarykidney    
    cell lineage
    cell lines leiomyosarcoma and adenocarcinoma cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • glucosamine/galactosamine-6-phosphate isomerase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to obesity (Hotta 2009)
    Variant & Polymorphism SNP associated to obesity risk (Hotta 2009)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS