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FLASH GENE
Symbol GNPDA2 contributors: mct - updated : 28-08-2010
HGNC name glucosamine-6-phosphate deaminase 2
HGNC id 21526
Location 4p12      Physical location : 44.704.168 - 44.728.612
Synonym name
  • glucosamine-6-phosphate isomerase
  • GlcN6P deaminase 2
  • Synonym symbol(s) 4921523I18Rik, SB52, GNP2
    EC.number 3.5.99.6
    DNA
    TYPE functioning gene
    STRUCTURE 24.45 kb     7 Exon(s)
    MAPPING cloned Y linked N status provisional
    Physical map
    KIAA1102 4p13-p11 cyclic nucleotide gated channel alpha 1 PHOX2B 4p12 paired-like homeobox 2b FLJ10525 4p14 hypothetical protein FLJ10525 LOC285429 4p14 hypothetical protein LOC285429 SLC30A9 4p13-p12 solute carrier family 30 (zinc transporter), member 9 ATP1BL1 4p15-q13 ATPase, Na+/K+ transporting, beta polypeptide-like 1 LOC389206 4 hypothetical gene supported by AK125953 ATP8A1 4p14-p12 ATPase, aminophospholipid transporter (APLT), Class I, type 8A, member 1 LOC389207 4 similar to ENSANGP00000012385 LOC345302 4p13 similar to ribosomal protein S2; 40S ribosomal protein S2 PGBD3P4 4p14 piggyBac transposable element derived 3 pseudogene 4 KCTD8 4p13 potassium channel tetramerisation domain containing 8 FLJ39576 4p13 hypothetical protein FLJ39576 FLJ13220 4p13 hypothetical protein FLJ13220 GNPDA2 4p13 glucosamine-6-phosphate deaminase 2 LOC391648 4 similar to ribosomal protein L4; 60S ribosomal protein L4; homologue of Xenopus ribosomal protein L1 GABRG1 4p14-q21.1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 GABRA2 4p13-p12 gamma-aminobutyric acid (GABA) A receptor, alpha 2 LOC256000 4p13 similar to ras-related C3 botulinum toxin substrate 1 isoform Rac1; rho family, small GTP binding protein Rac1 COX7B2 4p13 cytochrome c oxidase subunit VIIb2 GABRA4 4p14-p12 gamma-aminobutyric acid (GABA) A receptor, alpha 4 GABRB1 4p13-p12 gamma-aminobutyric acid (GABA) A receptor, beta 1 FLJ20502 4p12 hypothetical protein FLJ20502 ATP10D 4p13-q13.1 ATPase, Class V, type 10D CRN 4p13-p12 corin HOZFP 4p12 ovarian zinc finger protein CNGA1 4p14-q13 cyclic nucleotide gated channel alpha 1 LOC152519 4p12 hypothetical protein LOC152519 TXK 4p12 TXK tyrosine kinase
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    7 - 1939 - 276 - Arreola (2003)
    EXPRESSION
    Type
    constitutive of
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Endocrinepancreasislet of Langerhans   
    Nervousbraindiencephalonhypothalamus  
    Reproductivemale systemtestis   
    Urinarykidney    
    cell lineage
    cell lines leiomyosarcoma and adenocarcinoma cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    Homologene
    FAMILY
  • glucosamine/galactosamine-6-phosphate isomerase family
  • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism carbohydrate
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to obesity (Hotta 2009)
    Variant & Polymorphism SNP associated to obesity risk (Hotta 2009)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS